Catalysis of the reaction: squalene = triterpene.

The chemical reactions and pathways resulting in the breakdown of DNA, involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of deoxyribonucleotides.

The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one.

The chemical reactions and pathways resulting in the breakdown of DNA, involving the hydrolysis of terminal 3',5'-phosphodiester bonds in one or two strands of deoxyribonucleotides.

Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 1-N-acetylaminoglycoside. This is acetylation of the 1-amino group of the central deoxystreptamine ring.

Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + N-acetylaminoglycoside.

The removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur.

An incomplete microtubule containing 10 protofilaments that fuses with a complete microtubule called A tubule (containing 13 protofilaments) to form an axonemal outer doublet.

Catalysis of the reaction: oxidosqualene + H2O = arabidiol ((13R,14R,17E)-malabarica-17,21-diene-3beta,14-diol).

Catalysis of the cyclization of (S)-2,3-epoxysqualene to form a triterpene.

During DSBR via single-strand annealing, the removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur.

A phosphatidylinositol 3-kinase complex that contains a catalytic and a regulatory subunit of a phosphatidylinositol 3-kinase (PI3K) enzyme, plus one or more adaptor proteins. Class I PI3Ks phosphorylate phosphatidylinositol [PI], phosphatidylinositol-4-phosphate [PI(4)P] and phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2], and are divided into subclasses A and B according to the type of adaptor subunit with which they associate. The class I PI3K subfamily of genes comprises members in vertebrates, worm and fly, but none in yeast.

A protein complex capable of phosphatidylinositol 3-kinase activity and containing subunits of any phosphatidylinositol 3-kinase (PI3K) enzyme. These complexes are divided in three classes (called I, II and III) that differ for their presence across taxonomic groups and for the type of their constituents. Catalytic subunits of phosphatidylinositol 3-kinase enzymes are present in all 3 classes; regulatory subunits of phosphatidylinositol 3-kinase enzymes are present in classes I and III; adaptor proteins have been observed in class II complexes and may be present in other classes too.

Catalysis of the reaction: oxidosqualene = cucurbitadienol.

OBSOLETE. The identification and annealing of complementary base pairs in single-strand DNA.

A phosphatidylinositol 3-kinase complex that contains a catalytic subunit of a phosphatidylinositol 3-kinase (PI3K) enzyme and one or more adaptor proteins. There is no known obligatory regulatory subunit. The class II PI3K (PI3KC2) subfamily of genes has members in vertebrates, worm and fly, but none in yeast.

Catalysis of the reaction: squalene = tetrahymanol.

The part of a cell encompassing the intracellular environment and the plasma membrane; it excludes any external encapsulating structures.

Catalysis of the reaction: oxidosqualene = marneral.