Any process that activates or increases the frequency, rate or extent of cellular senescence.

The volume enclosed by the membrane of a chromaffin granule.

The volume enclosed by the membrane of an esterosome.

The assembly of a uropod by rearrangement of the cytoskeleton and overlying membrane.

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a uropod, a rigid membrane projection with related cytoskeletal components at the trailing edge of a lymphocyte or other cell in the process of migrating or being activated.

Binding to a steroid hormone.

Binding to a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene.

The process in which a uropod detaches from the cell substrate and retracts the rear of a migrating cell.

Catalysis of the hydrolysis of ester linkages within a double-stranded deoxyribonucleic acid molecule by creating internal breaks.

A protein complex which is capable of diamine N-acetyltransferase activity.

A protein complex which is capable of acetyltransferase activity.

The directed movement of the proteasome core complex (AKA core particle (CP)) from the cytoplasm into the nucleus.

The directed movement of substances into the nucleus.

A protein complex capable of catalyzing the transfer of a phosphate group from one position to another within a single molecule.

A protein dimer containing two STING monomers. It binds cyclic purine di-nucleotides. Activation of the sting complex by 2',5'-3'-5'-cyclic GMP-AMP activates nuclear transcription factor kB (NF-kB) and interferon regulatory factor 3 (IRF3) which then induce transcription of the genes encoding type I IFN and cytokines active in the innate immune response.

A protein complex capable of phosphomannomutase activity.

A protein complex capable of catalyzing the transfer of an iron-sulfur (Fe-S) cluster from one compound (donor) to another (acceptor).

Any positive regulation of proteasomal ubiquitin-dependent protein catabolic process that is involved in a cellular response to hypoxia.

Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.